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Tadalafil è un composto lipofilo con elevata affinità per PDE5 e scarsa interazione con altre isoforme enzimatiche. Il volume di distribuzione elevato conferma la capacità di penetrare nei compartimenti periferici. L’eliminazione biliare è predominante con metaboliti inattivi. L’effetto farmacologico si mantiene costante per più di un giorno. Per queste ragioni, cialis mg generico è associato a un profilo cinetico esteso con stabilità plasmatica.

CHOCO MUSEUM, GRANADA, NICARAGUA

What attracted my attention to this story was how an American man from NY ended up in the colonial town of Granada, Nicaragua as the owner of a hotel and featuring in the front entrance a museum dedicated to chocolate. I had to find out more about what inspires someone to leave their country to move to a foreign land and contribute to the culture and tourism in this way.  


FOOD FOR THOUGHT

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My choice to eat mostly nutrient-dense, fresh, vegetarian food a couple of years ago, has lead me into a path of discovering resources that could provide information, ideas and product features that keep the inventiveness of this particular cuisine flowing with new ideas. I have found these magazines to provide good reading on a variety of topics related to food and health, nourishing ideas using better grade products, and great glossy photos that inspire one to cook a new dish.

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